Tympanic membrane organ culture using cell culture well inserts engrafted with tympanic membrane tissue explants
نویسندگان
چکیده
منابع مشابه
Tympanic membrane organ culture using cell culture well inserts engrafted with tympanic membrane tissue explants.
Tissue engineering approaches using growth factors and various materials for repairing chronic perforations of the tympanic membrane are being developed, but there are surprisingly few relevant tissue culture models available to test new treatments. Here, we present a simple three-dimensional model system based on micro-dissecting the rat tympanic membrane umbo and grafting it into the membrane...
متن کاملFirst branchial cleft; Congenital anomalies; Facial nerve; Tympanic membrane duplication, Tympanic membrane triplication
Methods: We conducted a retrospective chart review of all patients consecutively referred to the senior authors at a tertiary-care Pediatric Otolaryngology clinic for fi rst branchial cleft anomalies over a 14-year period. Patients underwent computerized tomography scan with contrast, otoscopy plus tympanic microsurgery, when indicated (29%), methylene blue mapping of the cutaneous opening, whe...
متن کاملOutlook for Tissue Engineering of the Tympanic Membrane
Tympanic membrane perforation is a common problem leading to hearing loss. Despite the autoregenerative activity of the eardrum, chronic perforations require surgery using different materials, from autologous tissue - fascia, cartilage, fat or perichondrium - to paper patch. However, both, surgical procedures (myringoplasty or tympanoplasty) and the materials employed, have a number of limitati...
متن کاملThe concept of an artificial tympanic membrane.
A review is given of the development of the concept of an artificial tympanic membrane. Starting with homologous tympanic membranes we compared biodegradable collagen materials (homologous and heterologous) and biodegradable synthetic materials, poly-glycolic acid, poly-lactic acid and poly-alpha-amino acids. As a non-degradable material microporous PTFE and bisphenol-A poly (carbonate) were in...
متن کاملTwo Mathematical Models for the Tympanic Membrane
In this project we present two mathematical models for the human tympanic membrane. The eardrum can be viewed as an example of the vibrating drum problem. In the first model, we treat the tympanic membrane as a rectangular region. In the second model the tympanic membrane is considered as a disk. Both models use a wave equations. We study the impact of changes in the membrane tension related to...
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ژورنال
عنوان ژورنال: BioTechniques
سال: 2017
ISSN: 1940-9818,0736-6205
DOI: 10.2144/000114523